What is sepsis and how can practitioners and parents spot the early warning signs? Meredith Jones Russell reports

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Sepsis, the so-called ‘silent killer’, is one of the most common causes of death in the UK, thought to affect around 250,000 people a year and claim the lives of 46,000 – including children – in England alone. It can also result in the loss of limbs and organ failure. Sepsis deaths in England’s hospitals have risen by more than a third in two years, according to data from the Dr Foster research unit at Imperial College in London. However, definite statistics on the number of sepsis deaths vary as there is no official registry.

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