The majority of staff at the Norton College and Fir Vale nurseries are to be redeployed to Hillsborough College and Sheffield City.
The nurseries are the latest in a long line of campus-based settings that have been earmarked for closure following budget cuts.
Jason Pepper, executive director of finance and resources at Sheffield College, said, 'The college cannot continue to subsidise these facilities in the current climate, so it is with regret that both nurseries will close from September 2010.'
Denise Bertuchi, assistant national officer at Unison, said, 'Education does not stop at the school gates and the impact will be felt by the community and the most vulnerable in society, which is ironic given David Cameron's promotion of the Big Society. We believe this is just the tip of the iceberg, as over the last week we have heard of at least ten colleges announcing closures. The biggest hit will be to low-paid women who may lose their livelihood or suffer a lack of childcare facilities.'